ProteoNic and Wageningen University and Research Centre, AFSG sign Research License and collaboration

Today ProteoNic and Wageningen University and Research Centre (Wageningen UR), Agrotechnology and Food Sciences Group announce their collaboration on the development and expression of enzymes in fungal host systems. ProteoNic has granted a Research License and will provide its expertise in construct design and protein expression optimization. Wageningen UR will apply ProteoNic’s UNic™ expression enhancement technology in projects in which industrial enzymes are expressed in fungal host systems.

ProteoNic broadens its UNic™ expression technology toolbox

ProteoNic is a supplier of specialized products and services in the field of expression enhancement founded on its leading expertise in optimizing messenger RNA usage. Today, ProteoNic is proud to announce it has launched UNic-YTee™, its yeast specific Translation Enhancement Element (TEE). UNic-YTee™ is part of the company’s existing UNic™ expression technology toolbox already covering mammalian, fungal and plant production host systems. The UNic™ products boost translation efficiency and are complementary to transcription enhancing and other common expression technologies. ProteoNic achieved solid proof of concept increasing expression yields up to a factor 7 in Saccharomyces cerevisiae for several commercially relevant proteins.

ProteoNic and ModiQuest announce collaboration

Today ProteoNic and ModiQuest announce their collaboration on antibody expression in mammalian cell culture for use in diagnostic and therapeutic product development and manufacturing. ProteoNic will provide its expertise in construct design and protein expression optimization. ModiQuest will apply its proprietary vectors systems and expertise in high throughput production of high level expressing mammalian cell lines in combination with the UNic™ expression technology to manufacture its commercial antibodies in mammalian cell lines.

ProteoNic presents at the Advanced International Biotechnology Courses

On March 30 – April 4 the “Advanced International Biotechnology Courses” will be held at the NH Leeuwenhorst Congres Centre in Noordwijkerhout and partially at the Leiden Bio Science Park, the Netherlands. In addition to sponsoring these full time, advanced professional courses, ProteoNic will give a lecture on “Upstream modification for enhanced production yield” on April 1, 2008 as part of the “Advances in Cell Culture” course. Other presenters include Xendo, Merck GmbH, Serono, BioCult and the University of Southern California.

ProteoNic announces collaboration with TNO

Today ProteoNic announces it has entered into a collaboration with TNO to further commercialize and validate ProteoNic’s UNic™ expression technology in mammalian host systems. ProteoNic will provide expertise in construct design and protein expression optimization. TNO will apply this expertise and the UNic™ expression technology to manufacture commercial proteins in CHO cell lines.